Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice

Lipin proteins (lipin 1, 2, and 3) regulate glycerolipid homeostasis by acting as phosphatidic acid phosphohydrolase (PAP) enzymes in the TG synthesis pathway and by regulating DNA-bound transcription factors to control gene transcription. Hepatic PAP activity could contribute to hepatic fat accumul...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Lipid Res
Egile Nagusiak: Schweitzer, George G., Chen, Zhouji, Gan, Connie, McCommis, Kyle S., Soufi, Nisreen, Chrast, Roman, Mitra, Mayurranjan S., Yang, Kui, Gross, Richard W., Finck, Brian N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373742/
https://ncbi.nlm.nih.gov/pubmed/25722343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055962
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak