The combination of ezetimibe and ursodiol promotes fecal sterol excretion and reveals a G5G8-independent pathway for cholesterol elimination

Previous studies suggest an interdependent relationship between liver and intestine for cholesterol elimination from the body. We hypothesized that a combination of ursodiol (Urso) and ezetimibe (EZ) could increase biliary secretion and reduce cholesterol reabsorption, respectively, to promote chole...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Wang, Yuhuan, Liu, Xiaoxi, Pijut, Sonja S., Li, Jianing, Horn, Jamie, Bradford, Emily M., Leggas, Markos, Barrett, Terrence A., Graf, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373739/
https://ncbi.nlm.nih.gov/pubmed/25635125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M053454
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