Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity

Liver X receptor (LXR)α and LXRβ play key roles in hepatic de novo lipogenesis through their regulation of lipogenic genes, including sterol regulatory element-binding protein (SREBP)-1c and carbohydrate responsive element-binding protein (ChREBP). LXRs activate lipogenic gene transcription in respo...

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Vydáno v:J Lipid Res
Hlavní autoři: Bindesbøll, Christian, Fan, Qiong, Nørgaard, Rikke C., MacPherson, Laura, Ruan, Hai-Bin, Wu, Jing, Pedersen, Thomas Å., Steffensen, Knut R., Yang, Xiaoyong, Matthews, Jason, Mandrup, Susanne, Nebb, Hilde I., Grønning-Wang, Line M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373736/
https://ncbi.nlm.nih.gov/pubmed/25724563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M049130
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