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Nuclear Receptor Liver X Receptor Is O-GlcNAc-modified in Response to Glucose

Post-translational modification of nucleocytoplasmic proteins by O-linked β-N-acetylglucosamine (O-GlcNAc) has for the last 25 years emerged as an essential glucose-sensing mechanism. The liver X receptors (LXRs) function as nutritional sensors for cholesterol-regulating lipid metabolism, glucose ho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Anthonisen, Elin Holter, Berven, Lise, Holm, Sverre, Nygård, Maria, Nebb, Hilde I., Grønning-Wang, Line M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804318/
https://ncbi.nlm.nih.gov/pubmed/19933273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.082685
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