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Strategies to fine-map genetic associations with lipid levels by combining epigenomic annotations and liver-specific transcription profiles

Characterization of the epigenome promises to yield the functional elements buried in the human genome sequence, thus helping to annotate non-coding DNA polymorphisms with regulatory functions. Here, we develop two novel strategies to combine epigenomic data with transcriptomic profiles in humans or...

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Detalhes bibliográficos
Publicado no:Genomics
Main Authors: Lo, Ken Sin, Vadlamudi, Swarooparani, Fogarty, Marie P., Mohlke, Karen L., Lettre, Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373602/
https://ncbi.nlm.nih.gov/pubmed/24997396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2014.04.006
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