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Design, Synthesis, and Evaluation of Novel Small Molecule Inhibitors of the Influenza Virus Protein NS1

Influenza is a continuing world-wide public health problem that causes significant morbidity and mortality during seasonal epidemics and sporadic pandemics. The existing vaccination program is variably effective from year to year, and drug resistance to available antivirals is a growing problem, mak...

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Vydáno v:Bioorg Med Chem
Hlavní autoři: Jablonski, Joseph J., Basu, Dipwanita, Engel, Daniel A., Geysen, H. Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373408/
https://ncbi.nlm.nih.gov/pubmed/22099257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.10.026
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