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The loss of Tm7sf gene accelerates skin papilloma formation in mice

The 3β-hydroxysterol Δ14-reductase, encoded by the Tm7sf2 gene, is an enzyme involved in cholesterol biosynthesis. Cholesterol and its derivatives control epidermal barrier integrity and are protective against environmental insults. To determine the role of the gene in skin cholesterol homeostasis,...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Bellezza, I., Gatticchi, L., Sordo, R. del, Peirce, M. J., Sidoni, A., Roberti, R., Minelli, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372794/
https://ncbi.nlm.nih.gov/pubmed/25804527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09471
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