LIMK1 Regulates Long-Term Memory and Synaptic Plasticity via the Transcriptional Factor CREB

Deletion of the LIMK1 gene is associated with Williams syndrome, a unique neurodevelopmental disorder characterized by severe defects in visuospatial cognition and long-term memory (LTM). However, whether LIMK1 contributes to these deficits remains elusive. Here, we show that LIMK1-knockout (LIMK1(−...

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Pubblicato in:Mol Cell Biol
Autori principali: Todorovski, Zarko, Asrar, Suhail, Liu, Jackie, Saw, Ner Mu Nar, Joshi, Krutika, Cortez, Miguel A., Snead, O. Carter, Xie, Wei, Jia, Zhengping
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372699/
https://ncbi.nlm.nih.gov/pubmed/25645926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01263-14
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