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HSP105 Recruits Protein Phosphatase 2A To Dephosphorylate β-Catenin

The Wnt/β-catenin pathway causes accumulation of β-catenin in the cytoplasm and its subsequent translocation into the nucleus to initiate the transcription of the target genes. Without Wnt stimulation, β-catenin forms a complex with axin (axis inhibitor), adenomatous polyposis coli (APC), casein kin...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Yu, Nancy, Kakunda, Michael, Pham, Victoria, Lill, Jennie R., Du, Pan, Wongchenko, Matthew, Yan, Yibing, Firestein, Ron, Huang, XiaoDong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372692/
https://ncbi.nlm.nih.gov/pubmed/25645927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01307-14
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