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Preclinical imaging evaluation of novel TSPO-PET ligand 2-(5,7-diethyl-2-(4-(2-[(18)F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([(18)F]VUIIS1008) in glioma
PURPOSE: Translocator protein (TSPO) concentrations are elevated in glioma, suggesting a role for TSPO Positron Emission Tomography (PET) imaging in this setting. In preclinical PET studies, we evaluated a novel, high-affinity TSPO PET ligand, [(18)F]VUIIS1008, in healthy mice and glioma-bearing rat...
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| Vydáno v: | Mol Imaging Biol |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372299/ https://ncbi.nlm.nih.gov/pubmed/24845529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-014-0743-2 |
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