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2-substituted Nγ-glutamylanilides as novel probes of ASCT2 with improved potency

Herein, we report the discovery and structure-activity relationships (SAR) of 2-substituted glutamylanilides as novel probes of the steric environment comprising the amino acid binding domain of alanine-serine-cysteine transporter subtype 2 (ASCT2). Focused library development led to three novel, hi...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Bioorg Med Chem Lett
Päätekijät: Schulte, Michael L., Dawson, Eric S., Saleh, Sam. A., Cuthbertson, Madison L., Manning, H. Charles
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372298/
https://ncbi.nlm.nih.gov/pubmed/25435145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.10.098
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