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2-substituted Nγ-glutamylanilides as novel probes of ASCT2 with improved potency
Herein, we report the discovery and structure-activity relationships (SAR) of 2-substituted glutamylanilides as novel probes of the steric environment comprising the amino acid binding domain of alanine-serine-cysteine transporter subtype 2 (ASCT2). Focused library development led to three novel, hi...
Tallennettuna:
Julkaisussa: | Bioorg Med Chem Lett |
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Päätekijät: | , , , , |
Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
2014
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372298/ https://ncbi.nlm.nih.gov/pubmed/25435145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.10.098 |
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