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QSAR based model for discriminating EGFR inhibitors and non-inhibitors using Random forest

BACKGROUND: Epidermal Growth Factor Receptor (EGFR) is a well-characterized cancer drug target. In the past, several QSAR models have been developed for predicting inhibition activity of molecules against EGFR. These models are useful to a limited set of molecules for a particular class like quinazo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biol Direct
Egile Nagusiak: Singh, Harinder, Singh, Sandeep, Singla, Deepak, Agarwal, Subhash M, Raghava, Gajendra P S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372225/
https://ncbi.nlm.nih.gov/pubmed/25880749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-015-0046-9
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