Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding protein.

Cells from a subset of patients with the DNA-repair-defective disease xeroderma pigmentosum complementation group E (XP-E) are known to lack a DNA damage-binding (DDB) activity. Purified human DDB protein was injected into XP-E cells to test whether the DNA-repair defect in these cells is caused by...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Keeney, S, Eker, A P, Brody, T, Vermeulen, W, Bootsma, D, Hoeijmakers, J H, Linn, S
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1994
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43721/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8171034/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.9.4053
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