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Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding protein.

Cells from a subset of patients with the DNA-repair-defective disease xeroderma pigmentosum complementation group E (XP-E) are known to lack a DNA damage-binding (DDB) activity. Purified human DDB protein was injected into XP-E cells to test whether the DNA-repair defect in these cells is caused by...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Keeney, S, Eker, A P, Brody, T, Vermeulen, W, Bootsma, D, Hoeijmakers, J H, Linn, S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43721/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8171034/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.9.4053
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