CYB5A polymorphism increases androgens and reduces risk of rheumatoid arthritis in women

INTRODUCTION: Rheumatoid arthritis (RA) is characterized by decreased androgen levels, which was the first hormonal abnormality described. Several studies indicated that steroidogenesis is directed towards endogenous glucocorticoids at the expense of androgens. The decisive step governing androgen s...

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Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Stark, Klaus, Straub, Rainer H, Rovenský, Jozef, Blažičková, Stanislava, Eiselt, Gabriele, Schmidt, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372052/
https://ncbi.nlm.nih.gov/pubmed/25890314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0574-9
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