CYB5A polymorphism increases androgens and reduces risk of rheumatoid arthritis in women

INTRODUCTION: Rheumatoid arthritis (RA) is characterized by decreased androgen levels, which was the first hormonal abnormality described. Several studies indicated that steroidogenesis is directed towards endogenous glucocorticoids at the expense of androgens. The decisive step governing androgen s...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Stark, Klaus, Straub, Rainer H, Rovenský, Jozef, Blažičková, Stanislava, Eiselt, Gabriele, Schmidt, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372052/
https://ncbi.nlm.nih.gov/pubmed/25890314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0574-9
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