Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels

TMEM16A (transmembrane protein 16) (Anoctamin-1) forms a calcium-activated chloride channel (CaCC) that regulates a broad array of physiological properties in response to changes in intracellular calcium concentration. Although known to conduct anions according to the Eisenman type I selectivity seq...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Peters, Christian J., Yu, Haibo, Tien, Jason, Jan, Yuh Nung, Li, Min, Jan, Lily Yeh
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371966/
https://ncbi.nlm.nih.gov/pubmed/25733897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502291112
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki