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Mutation of a single residue in the ba(3) oxidase specifically impairs protonation of the pump site

The ba(3)-type cytochrome c oxidase from Thermus thermophilus is a membrane-bound protein complex that couples electron transfer to O(2) to proton translocation across the membrane. To elucidate the mechanism of the redox-driven proton pumping, we investigated the kinetics of electron and proton tra...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: von Ballmoos, Christoph, Gonska, Nathalie, Lachmann, Peter, Gennis, Robert B., Ädelroth, Pia, Brzezinski, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371939/
https://ncbi.nlm.nih.gov/pubmed/25733886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422434112
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