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Single mutations that redirect internal proton transfer in the ba(3) oxidase from Thermus thermophilus

The ba(3)-type cytochrome c oxidase from Thermus thermophilus is a membrane-bound proton pump. Results from earlier studies have shown that with the aa(3)-type oxidases proton uptake to the catalytic site and “pump site” occur simultaneously. However, with the ba(3) oxidase the pump site is loaded b...

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Publicado en:Biochemistry
Autores principales: Smirnova, Irina, Chang, Hsin-Yang, von Ballmoos, Christoph, Ädelroth, Pia, Gennis, Robert B., Brzezinski, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282493/
https://ncbi.nlm.nih.gov/pubmed/24004023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4008726
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