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Quorum-sensing Salmonella selectively trigger protein expression within tumors
Salmonella that secrete anticancer proteins have the potential to eliminate tumors, but nonspecific expression causes damage to healthy tissue. We hypothesize that Salmonella, integrated with a density-dependent switch, would only express proteins in tightly packed colonies within tumors. To test th...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371937/ https://ncbi.nlm.nih.gov/pubmed/25737556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414558112 |
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