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The hunt for origins of DNA replication in multicellular eukaryotes

Origins of DNA replication (ORIs) occur at defined regions in the genome. Although DNA sequence defines the position of ORIs in budding yeast, the factors for ORI specification remain elusive in metazoa. Several methods have been used recently to map ORIs in metazoan genomes with the hope that featu...

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Détails bibliographiques
Publié dans:F1000Prime Rep
Auteurs principaux: Urban, John M., Foulk, Michael S., Casella, Cinzia, Gerbi, Susan A.
Format: Artigo
Langue:Inglês
Publié: Faculty of 1000 Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371235/
https://ncbi.nlm.nih.gov/pubmed/25926981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/P7-30
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