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miRNA Expression Profile and Involvement of Let-7d-APP in Aged Rats with Isoflurane-Induced Learning and Memory Impairment

MicroRNAs (miRNAs) play a key role in different nervous system diseases. We sought to determine the role of miRNAs in isoflurane-induced learning and memory impairment in aged rats. Male Sprague-Dawley (SD) rats of 18 month were randomly assigned to control group (exposed to mock anesthesia), 2-hour...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Luo, Ting, Yin, Shuzhou, Shi, Rong, Xu, Chengshi, Wang, Yun, Cai, Jun, Yue, Yun, Wu, Anshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370901/
https://ncbi.nlm.nih.gov/pubmed/25799420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119336
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