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Isoflurane-induced spatial memory impairment by a mechanism independent of amyloid-beta levels and tau protein phosphorylation changes in aged rats

OBJECTIVES: The molecular mechanism of postoperative cognitive dysfunction is largely unknown. Isoflurane has been shown to promote Alzheimer’s disease neuropathogenesis. We set out to determine whether the effect of isoflurane on spatial memory is associated with amyloid-beta (A-beta) levels and ta...

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Detalhes bibliográficos
Main Authors: Liu, Weiran, Xu, Jie, Wang, Hui, Xu, Chengshi, Ji, Chao, Wang, Yun, Feng, Chunsheng, Zhang, Xuena, Xu, Zhipeng, Wu, Anshi, Xie, Zhongcong, Yue, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971391/
https://ncbi.nlm.nih.gov/pubmed/22196855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/1743132811Y.0000000047
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