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Blood coagulation factor XIa binds specifically to a site on activated human platelets distinct from that for factor XI.
Binding of 125I-Factor XIa to platelets required the presence of high molecular weight kininogen, was enhanced when platelets were stimulated with thrombin, and reached a plateau after 4-6 min of incubation at 37 degrees C. Factor XIa binding was specific: 50- to 100-fold molar excesses of unlabeled...
Enregistré dans:
| Publié dans: | J Clin Invest |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
1984
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC437065/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6609936/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111361 |
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