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Developmental Exposure to Estrogen Alters Differentiation and Epigenetic Programming in a Human Fetal Prostate Xenograft Model

Prostate cancer is the most frequent non-cutaneous malignancy in men. There is strong evidence in rodents that neonatal estrogen exposure plays a role in the development of this disease. However, there is little information regarding the effects of estrogen in human fetal prostate tissue. This study...

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Veröffentlicht in:PLoS One
Hauptverfasser: Saffarini, Camelia M., McDonnell-Clark, Elizabeth V., Amin, Ali, Huse, Susan M., Boekelheide, Kim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370592/
https://ncbi.nlm.nih.gov/pubmed/25799167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122290
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