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Retroviruses Hijack Chromatin Loops to Drive Oncogene Expression and Highlight the Chromatin Architecture around Proto-Oncogenic Loci

The majority of the genome consists of intergenic and non-coding DNA sequences shown to play a major role in different gene regulatory networks. However, the specific potency of these distal elements as well as how these regions exert function across large genomic distances remains unclear. To addre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pattison, Jillian M., Wright, Jason B., Cole, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370588/
https://ncbi.nlm.nih.gov/pubmed/25799187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120256
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