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Chronic blockade of endothelin A and B receptors using macitentan in experimental renovascular disease
BACKGROUND: Emerging research has identified the endothelin (ET)-1 pathway as a potential target for novel renoprotective therapies. We recently showed that selective ET-A receptor antagonism in chronic renovascular disease (RVD) improves renal function and reduces renal injury. Although ET-A and -B...
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Publicado no: | Nephrol Dial Transplant |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4370292/ https://ncbi.nlm.nih.gov/pubmed/25438341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfu361 |
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