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Endothelin-A receptor blockade slows the progression of renal injury in experimental renovascular disease
Endothelin (ET)-1, a potent renal vasoconstrictor with mitogenic properties, is upregulated by ischemia and has been shown to induce renal injury via the ET-A receptor. The potential role of ET-A blockade in chronic renovascular disease (RVD) has not, to our knowledge, been previously reported. We h...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129888/ https://ncbi.nlm.nih.gov/pubmed/21478482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00089.2011 |
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