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MicroRNA100 Inhibits Self-Renewal of Breast Cancer Stem–like Cells and Breast Tumor Development

miRNAs are essential for self-renewal and differentiation of normal and malignant stem cells by regulating the expression of key stem cell regulatory genes. Here, we report evidence implicating the miR100 in self-renewal of cancer stem-like cells (CSC). We found that miR100 expression levels relate...

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Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: Deng, Lu, Shang, Li, Bai, Shoumin, Chen, Ji, He, Xueyan, Martin-Trevino, Rachel, Chen, Shanshan, Li, Xiao-yan, Meng, Xiaojie, Yu, Bin, Wang, Xiaolin, Liu, Yajing, McDermott, Sean P., Ariazi, Alexa E., Ginestier, Christophe, Ibarra, Ingrid, Ke, Jia, Luther, Tahra, Clouthier, Shawn G., Xu, Liang, Shan, Ge, Song, Erwei, Yao, Herui, Hannon, Gregory J., Weiss, Stephen J., Wicha, Max S., Liu, Suling
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370193/
https://ncbi.nlm.nih.gov/pubmed/25217527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3710
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