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Molecular basis of hypoxanthine-guanine phosphoribosyltransferase deficiency in a patient with the Lesch-Nyhan syndrome.

We have investigated the molecular basis of hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency in a patient who presented with the Lesch-Nyhan syndrome. A catalytically incompetent form of HPRT has been isolated from this patient's erythrocytes and lymphoblasts. This enzyme varian...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wilson, J M, Kelley, W N
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1983
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC436995/
https://ncbi.nlm.nih.gov/pubmed/6853716
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