Impact of phosphomimetic and non-phosphorylatable mutations of phospholemman on L-type calcium channels gating in HEK 293T cells

BACKGROUND: Phospholemman (PLM) is an important phosphorylation substrate for protein kinases A and C in the heart. Until now, the association between PLM phosphorylation status and L-type calcium channels (LTCCs) gating has not been fully understood. We investigated the kinetics of LTCCs in HEK 293...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Guo, Kai, Wang, Yue-Peng, Zhou, Zhi-Wen, Jiang, Yi-Bo, Li, Wei, Chen, Xiao-Meng, Li, Yi-Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369820/
https://ncbi.nlm.nih.gov/pubmed/25656605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12484
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