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Pyridoxal phosphate as an antisickling agent in vitro.

Although pyridoxal phosphate is known to inhibit gelation of purified hemoglobin S, antisickling activity has never been demonstrated for intact erythrocytes. We incubated washed erythrocytes at 37 degrees C either in buffer alone, or with added pyridoxal phosphate or pyridoxal, washed these cells,...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kark, J A, Tarassoff, P G, Bongiovanni, R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436982/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6853710/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110871
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