Attenuation of microRNA-16 derepresses the cyclins D1, D2 and E1 to provoke cardiomyocyte hypertrophy

Cyclins/retinoblastoma protein (pRb) pathway participates in cardiomyocyte hypertrophy. MicroRNAs (miRNAs), the endogenous small non-coding RNAs, were recognized to play significant roles in cardiac hypertrophy. But, it remains unknown whether cyclin/Rb pathway is modulated by miRNAs during cardiac...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Huang, Shuai, Zou, Xiao, Zhu, Jie-Ning, Fu, Yong-Heng, Lin, Qiu-Xiong, Liang, Ye-You, Deng, Chun-Yu, Kuang, Su-Juan, Zhang, Meng-Zhen, Liao, Yu-Lin, Zheng, Xi-Long, Yu, Xi-Yong, Shan, Zhi-Xin
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369817/
https://ncbi.nlm.nih.gov/pubmed/25583328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12445
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