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The role of PTPN22 risk variant in the development of autoimmunity: Finding common ground between mouse and man

The PTPN22 1858T variant was among the first single nucleotide polymorphisms (snp) to be associated with multiple autoimmune diseases. As a coding variant within the tyrosinephosphatase, Lyp, known to participate in antigen receptor signaling, the impact of this variant on the immune response and ro...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Rawlings, David J., Dai, Xuezhi, Buckner, Jane H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369788/
https://ncbi.nlm.nih.gov/pubmed/25795788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403034
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