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Leptin ameliorates ischemic necrosis of the femoral head in rats with obesity induced by a high-fat diet

Obesity is a risk factor for ischemic necrosis of the femoral head (INFH). The purpose of this study was to determine if leptin treatment of INFH stimulates new bone formation to preserve femoral head shape in rats with diet-induced obesity. Rats were fed a high-fat diet (HFD) or normal chow diet (N...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zhou, Lu, Jang, Kyu Yun, Moon, Young Jae, Wagle, Sajeev, Kim, Kyoung Min, Lee, Kwang Bok, Park, Byung-Hyun, Kim, Jung Ryul
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369691/
https://ncbi.nlm.nih.gov/pubmed/25797953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09397
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