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Leptin ameliorates ischemic necrosis of the femoral head in rats with obesity induced by a high-fat diet

Obesity is a risk factor for ischemic necrosis of the femoral head (INFH). The purpose of this study was to determine if leptin treatment of INFH stimulates new bone formation to preserve femoral head shape in rats with diet-induced obesity. Rats were fed a high-fat diet (HFD) or normal chow diet (N...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Lu, Jang, Kyu Yun, Moon, Young Jae, Wagle, Sajeev, Kim, Kyoung Min, Lee, Kwang Bok, Park, Byung-Hyun, Kim, Jung Ryul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369691/
https://ncbi.nlm.nih.gov/pubmed/25797953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09397
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