Hypothalamic AgRP Neurons and the Central Melanocortin System are Crucial Mediators of Leptin's Anti-Diabetic Actions

The adipocyte hormone leptin has potent beneficial effects on glucose metabolism via actions in the arcuate nucleus of the hypothalamus (ARC). However, the requirement of specific subgroups of neurons within the ARC in mediating leptin's anti-diabetic actions is unknown. Here we generated diabe...

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Udgivet i:Cell Rep
Main Authors: Gonçalves, Gabriel H. M., Li, Wenjing, Garcia, Adriana V. C.-G., Figueiredo, Mariana S., Bjørbæk, Christian
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369586/
https://ncbi.nlm.nih.gov/pubmed/24813890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.010
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