Ether Link Cleavage Is the Major Pathway of Iodothyronine Metabolism in the Phagocytosing Human Leukocyte and also Occurs In Vivo in the Rat

These studies were performed to test the hypothesis that ether link cleavage (ELC) is an important pathway for the metabolism of thyroxine (T(4)) in the phagocytosing human leukocyte. When tyrosyl ring-labeled [(125)I]T(4)([Tyr(125)I]T(4)) was incubated with phagocytosing leukocytes, 50% of the degr...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Burger, Albert G., Engler, Dennis, Buergi, Ulrich, Weissel, Michael, Steiger, Gertraud, Ingbar, Sidney H., Rosin, Richard E., Babior, Bernard M.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1983
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436951/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6833495/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110848
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