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Degradation of Thyroid Hormones by Phagocytosing Human Leukocytes

Thyroxine (T(4)) and triiodothyronine (T(9)) are rapidly degraded by a purified preparation of myeloperoxidase (MPO) and H(2)O(2) with the formation of iodide and material which remains at the origin on paper chromatography. Deiodination by MPO and H(2)O(2) occurs more readily at pH 7.0 than at pH 5...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Klebanoff, Seymour J., Green, William L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1973
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302227/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4629909/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107174
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