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Degradation of Thyroid Hormones by Phagocytosing Human Leukocytes

Thyroxine (T(4)) and triiodothyronine (T(9)) are rapidly degraded by a purified preparation of myeloperoxidase (MPO) and H(2)O(2) with the formation of iodide and material which remains at the origin on paper chromatography. Deiodination by MPO and H(2)O(2) occurs more readily at pH 7.0 than at pH 5...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Klebanoff, Seymour J., Green, William L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1973
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302227/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4629909/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107174
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