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Degradation of Thyroid Hormones by Phagocytosing Human Leukocytes

Thyroxine (T(4)) and triiodothyronine (T(9)) are rapidly degraded by a purified preparation of myeloperoxidase (MPO) and H(2)O(2) with the formation of iodide and material which remains at the origin on paper chromatography. Deiodination by MPO and H(2)O(2) occurs more readily at pH 7.0 than at pH 5...

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Detalhes bibliográficos
Main Authors: Klebanoff, Seymour J., Green, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC302227/
https://ncbi.nlm.nih.gov/pubmed/4629909
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