Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and Stat5a

Progesterone (P4) has emerged as an important hormone regulating mammary stem cell populations. In breast cancer, P4 and synthetic analogs increase the number of stem-like cells within luminal estrogen receptor (ER) and progesterone receptor (PR) positive breast cancers. These cells gain expression...

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Pubblicato in:Oncogene
Autori principali: Finlay-Schultz, Jessica, Cittelly, Diana M., Hendricks, Peter, Patel, Purvi, Kabos, Peter, Jacobsen, Britta M., Richer, Jennifer K., Sartorius, Carol A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369481/
https://ncbi.nlm.nih.gov/pubmed/25241899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.298
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