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Local knockdown of the Na(V)1.6 sodium channel reduces pain behaviors, sensory neuron excitability, and sympathetic sprouting in rat models of neuropathic pain
In the spinal nerve ligation model of neuropathic pain, as in other pain models, abnormal spontaneous activity of myelinated sensory neurons occurs early and is essential for establishing pain behaviors and other pathologies. Sympathetic sprouting into the dorsal root ganglion (DRG) is observed afte...
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| Published in: | Neuroscience |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369447/ https://ncbi.nlm.nih.gov/pubmed/25686526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.02.010 |
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