Genetic polymorphisms in DNA repair and oxidative stress pathways may modify the association between body size and postmenopausal breast cancer

PURPOSE: Obesity is associated with increased bioavailability of estrogen, hyperinsulemia and chronic inflammation, all of which may promote tumor growth. Given DNA repair and oxidative stress pathways may work together with these mechanisms to influence carcinogenesis, we hypothesized that genetic...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Ann Epidemiol
Egile Nagusiak: McCullough, Lauren E., Eng, Sybil M., Bradshaw, Patrick T., Cleveland, Rebecca J., Steck, Susan E., Terry, Mary Beth, Shen, Jing, Crew, Katherine D., Rossner, Pavel, Ahn, Jiyoung, Ambrosone, Christine B., Teitelbaum, Susan L., Neugut, Alfred I., Santella, Regina M., Gammon, Marilie D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369423/
https://ncbi.nlm.nih.gov/pubmed/25703993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.annepidem.2015.01.009
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