Genetic polymorphisms in DNA repair and oxidative stress pathways may modify the association between body size and postmenopausal breast cancer

PURPOSE: Obesity is associated with increased bioavailability of estrogen, hyperinsulemia and chronic inflammation, all of which may promote tumor growth. Given DNA repair and oxidative stress pathways may work together with these mechanisms to influence carcinogenesis, we hypothesized that genetic...

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Detaylı Bibliyografya
Yayımlandı:Ann Epidemiol
Asıl Yazarlar: McCullough, Lauren E., Eng, Sybil M., Bradshaw, Patrick T., Cleveland, Rebecca J., Steck, Susan E., Terry, Mary Beth, Shen, Jing, Crew, Katherine D., Rossner, Pavel, Ahn, Jiyoung, Ambrosone, Christine B., Teitelbaum, Susan L., Neugut, Alfred I., Santella, Regina M., Gammon, Marilie D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369423/
https://ncbi.nlm.nih.gov/pubmed/25703993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.annepidem.2015.01.009
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