OSCAR is a receptor for Surfactant Protein D that activates TNF-α release from human CCR2(+) inflammatory monocytes

Surfactant Protein D (SP-D) is critical for maintenance of lung homeostasis and provides a first line of defense to pathogens at mucosal surfaces. Polymorphisms in the SP-D-encoding gene SFTPD have been associated with chronic obstructive pulmonary disease and ulcerative colitis. Identification of t...

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Publicado en:J Immunol
Main Authors: Barrow, Alexander D., Palarasah, Yaseelan, Bugatti, Mattia, Holehouse, Alex S., Byers, Derek E., Holtzman, Michael J., Vermi, William, Skjødt, Karsten, Crouch, Erika, Colonna, Marco
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369396/
https://ncbi.nlm.nih.gov/pubmed/25716998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402289
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