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OSCAR is a receptor for Surfactant Protein D that activates TNF-α release from human CCR2(+) inflammatory monocytes
Surfactant Protein D (SP-D) is critical for maintenance of lung homeostasis and provides a first line of defense to pathogens at mucosal surfaces. Polymorphisms in the SP-D-encoding gene SFTPD have been associated with chronic obstructive pulmonary disease and ulcerative colitis. Identification of t...
Enregistré dans:
Publié dans: | J Immunol |
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Auteurs principaux: | , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369396/ https://ncbi.nlm.nih.gov/pubmed/25716998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402289 |
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