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Integromic Analysis of Genetic Variation and Gene Expression Identifies Networks for Cardiovascular Disease Phenotypes

BACKGROUND: Cardiovascular disease (CVD) reflects a highly coordinated complex of traits. Although genome-wide association studies have reported numerous single nucleotide polymorphisms (SNPs) to be associated with CVD, the role of most of these variants in disease processes remains unknown. METHODS...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Yao, Chen, Chen, Brian H., Joehanes, Roby, Otlu, Burcak, Zhang, Xiaoling, Liu, Chunyu, Huan, Tianxiao, Tastan, Oznur, Cupples, L. Adrienne, Meigs, James B., Fox, Caroline S., Freedman, Jane E., Courchesne, Paul, O’Donnell, Christopher J., Munson, Peter J., Keles, Sunduz, Levy, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369387/
https://ncbi.nlm.nih.gov/pubmed/25533967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.010696
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