Novel Curcumin Analog C66 Prevents Diabetic Nephropathy via JNK Pathway with the Involvement of p300/CBP-mediated Histone Acetylation

Glomerulosclerosis and interstitial fibrosis represent the key events in development of diabetic nephropathy (DN), with connective tissue growth factor (CTGF), plasminogen activator inhibitor-1 (PAI-1) and fibronectin 1 (FN-1) playing important roles in these pathogenic processes. To investigate whe...

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Pubblicato in:Biochim Biophys Acta
Autori principali: Wang, Yangwei, Wang, Yonggang, Luo, Manyu, Wu, Hao, Kong, Lili, Xin, Ying, Cui, Wenpeng, Zhao, Yunjie, Wang, Jingying, Liang, Guang, Miao, Lining, Cai, Lu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369325/
https://ncbi.nlm.nih.gov/pubmed/25446993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.11.006
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