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Crosstalk between Translesion Synthesis, Fanconi Anemia Network, and Homologous Recombination Repair Pathways in Interstrand DNA Crosslink Repair and Development of Chemoresistance

Bifunctional alkylating and platinum based drugs are chemotherapeutic agents used to treat cancer. These agents induce DNA adducts via formation of intrastrand or interstrand (ICL) DNA crosslinks, and DNA lesions of the ICL type are particularly toxic as they block DNA replication and/or DNA transcr...

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書目詳細資料
發表在:Mutat Res Rev Mutat Res
Main Authors: Haynes, Brittany, Saadat, Nadia, Myung, Brian, Shekhar, Malathy PV
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369322/
https://ncbi.nlm.nih.gov/pubmed/25795124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2014.11.005
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