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THE FORK AND THE KINASE: A DNA REPLICATION TALE FROM A CHK1 PERSPECTIVE
Replication fork progression is being continuously hampered by exogenously introduced and naturally occurring DNA lesions and other physical obstacles. The checkpoint kinase 1 (Chk1) is activated at replication forks that encounter damaged-DNA. Chk1 inhibits the initiation of new replication factori...
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| izdano v: | Mutat Res Rev Mutat Res |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369321/ https://ncbi.nlm.nih.gov/pubmed/25795119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2014.10.003 |
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